Cloniprazepam

Not to be confused with clonazepam, clonazolam, or clorazolam.

Cloniprazepam is a benzodiazepine derivative and a prodrug of clonazepam, 7-aminoclonazepam, and other metabolites.^[1][2]

Cloniprazepam

Clinical data
Other names	1-Cyclopropylmethylclonazepam, Kloniprazepam, 2-Chloro-7'-nitroprazepam
Drug class	Benzodiazepines
Legal status
Legal status	CA: Schedule IV DE: NpSG (Industrial and scientific use only) UK: Schedule 1
Identifiers
IUPAC name 5-(2-Chlorophenyl)-1-(cyclopropylmethyl)-7-nitro-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one
CAS Number	1998158-84-1 Y
PubChem CID	137700140
ChemSpider	68003855
UNII	YSL4SM8QYP
CompTox Dashboard (EPA)	DTXSID60893511
Chemical and physical data
Formula	C19H16ClN3O3
Molar mass	369.81 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C1N(CC2CC2)C3=CC=C([N+]([O-])=O)C=C3C(C4=CC=CC=C4Cl)=NC1
InChI InChI=1S/C19H16ClN3O3/c20-16-4-2-1-3-14(16)19-15-9-13(23(25)26)7-8-17(15)22(11-12-5-6-12)18(24)10-21-19/h1-4,7-9,12H,5-6,10-11H2 Key:CCSYKGYLSFXNTA-UHFFFAOYSA-N

Metabolic pathway of cloniprazepam

Some of the minor metabolites include 3-hydroxyclonazepam and 6-hydroxyclonazepam, 3-hydroxycloniprazepam and ketocloniprazepam with ketone group formed where 3-hydroxy group was.^[1]

It is a designer drug and an NPS (short for "new psychoactive substance").^[1] At the end of 2017, cloniprazepam was an uncontrolled substance in most of the countries.

See also

• Flutoprazepam
• Ro05-4082
• List of designer drugs
• List of benzodiazepines
• List of benzodiazepine designer drugs