Cloroqualone

Cloroqualone
Clinical data
Pregnancy; category	?;
Routes of; administration	?
ATC code	none;
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Elimination half-life	?
Excretion	?
Identifiers
	IUPAC name 3-(2,6-Dichlorophenyl)-2-ethyl-4-quinazolinone;
CAS Number	25509-07-3 ;
PubChem CID	63338;
DrugBank	? ;
ChemSpider	57005 ;
UNII	172D4Q6LOW;
ChEMBL	ChEMBL2106114 ;
CompTox Dashboard (EPA)	DTXSID10180201 ;
ECHA InfoCard	100.042.761
Chemical and physical data
Formula	C16H12Cl2N2O
Molar mass	319.19 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Clc3cccc(Cl)c3N/1C(=O)c2c(\N=C\1CC)cccc2;
	InChI InChI=1S/C16H12Cl2N2O/c1-2-14-19-13-9-4-3-6-10(13)16(21)20(14)15-11(17)7-5-8-12(15)18/h3-9H,2H2,1H3 ; Key:SONHVLIDLXLSOL-UHFFFAOYSA-N ;
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Cloroqualone is a quinazolinone-class GABAergic and is an analogue of methaqualone developed in the 1980s and marketed mainly in France and some other European countries. It has sedative and antitussive properties resulting from its agonist activity at the β subtype of the GABA_a receptor and sigma-1 receptor, and was sold either alone or in combination with other ingredients as a cough medicine. Cloroqualone has weaker sedative properties than methaqualone and was sold for its useful cough-suppressing effects, but was withdrawn from the French market in 1994 because of concerns about its potential for abuse and overdose.^[1]^[2]^[3]

Quick Facts Clinical data, Pregnancycategory ...

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[2]

[3]

Cloroqualone

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References

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