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Collagen-induced arthritis
Medical condition From Wikipedia, the free encyclopedia
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Collagen-induced arthritis (CIA) is a condition induced in mice (or rats) to study rheumatoid arthritis.[1]
CIA is induced in mice by injecting them with an emulsion of complete Freund's adjuvant and type II collagen.[2]
In rats, only one injection is needed, but mice are normally injected twice.[3]
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