Cortisone acetate

Cortisone acetate (brand names Adreson, Cortison, Cortisone, Cortisone Acetate, Cortone, Cortistab, Cortisyl, others) is a synthetic glucocorticoid corticosteroid and corticosteroid ester which is marketed (under prescription) in many countries throughout the world, including in the United States, the United Kingdom, and various other European countries.^[1][2][3] It is the C21 acetate ester of cortisone,^[1][2] and acts as a prodrug of cortisone in the body.^[4]

Cortisone acetate

Clinical data
Trade names	Adreson, Cortison, Cortisone, Cortisone Acetate, Cortone, Cortistab, Cortisyl, others
Other names	Cortisone 21-acetate; 17α,21-Dihydroxypregn-4-ene-3,11,20-trione 21-acetate
Drug class	Corticosteroid; Glucocorticoid
Identifiers
IUPAC name [2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
CAS Number	50-04-4
PubChem CID	5745
DrugBank	DB01380
ChemSpider	5543
UNII	883WKN7W8X
KEGG	D00973
ChEBI	CHEBI:3897
ChEMBL	ChEMBL1650
CompTox Dashboard (EPA)	DTXSID0022858
ECHA InfoCard	100.000.006
Chemical and physical data
Formula	C23H30O6
Molar mass	402.487 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(CC(=O)[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O
InChI InChI=1S/C23H30O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-17,20,28H,4-9,11-12H2,1-3H3/t16-,17-,20+,21-,22-,23-/m0/s1 Key:ITRJWOMZKQRYTA-RFZYENFJSA-N