Corynebacterium freneyi

Corynebacterium freneyi is a species of Gram-positive, non-motile, non-spore-forming, rod-shaped bacterium in the genus Corynebacterium. It was first described in 2001 by Renaud et al. based on α-glucosidase-positive strains related to Corynebacterium xerosis.^[1]

Corynebacterium freneyi
Scientific classification
Domain:	Bacteria
Kingdom:	Bacillati
Phylum:	Actinomycetota
Class:	Actinomycetia
Order:	Mycobacteriales
Family:	Corynebacteriaceae
Genus:	Corynebacterium
Species:	C. freneyi
Binomial name
Corynebacterium freneyi Renaud et al. 2001

Taxonomy

C. freneyi was initially identified from clinical isolates that exhibited α-glucosidase activity and biochemical profiles similar to C. xerosis. However, molecular analyses, including 16S rRNA gene sequencing and restriction fragment length polymorphism (RFLP) of the 16S-23S rRNA intergenic spacer region, demonstrated that C. freneyi is a distinct species.^[2]

Clinical significance

Although initially considered a rare isolate, C. freneyi has been implicated in various clinical specimens, including those from the female genital tract. Its pathogenic potential remains under investigation, but it has been associated with bacteremia and prosthetic valve endocarditis in isolated cases.^[2][3]

Type strain

The type strain of C. freneyi is CCUG 45704 (= CIP 106767 = DSM 44506 = JCM 12104).^[4]