Cyanonilutamide

Cyanonilutamide
Clinical data
Other names	RU-56279
Drug class	Nonsteroidal antiandrogen
Identifiers
	IUPAC name 4-(4,4-Dimethyl-2,5-dioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile;
CAS Number	143782-20-1 ;
PubChem CID	11162285;
ChemSpider	9337385;
UNII	6PAG4TC385;
ChEMBL	ChEMBL146858;
CompTox Dashboard (EPA)	DTXSID901143349 ;
Chemical and physical data
Formula	C13H10F3N3O2
Molar mass	297.237 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC1(C(=O)N(C(=O)N1)C2=CC(=C(C=C2)C#N)C(F)(F)F)C;
	InChI InChI=1S/C13H10F3N3O2/c1-12(2)10(20)19(11(21)18-12)8-4-3-7(6-17)9(5-8)13(14,15)16/h3-5H,1-2H3,(H,18,21); Key:CYCKLVAQENOQPG-UHFFFAOYSA-N;

Cyanonilutamide (developmental code name RU-56279) is a nonsteroidal antiandrogen which was never marketed.^[1]^[2] Both RU-56187 and RU-58841 appear to be prodrugs of cyanonilutamide in vivo in animals.^[2] It has relatively low affinity for the androgen receptor but nonetheless shows significant antiandrogenic activity in animals.^[2]

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See also