Cyanophycin synthase (L-arginine-adding)

Cyanophycin synthase (L-arginine-adding) (EC 6.3.2.30, CphA, CphA1, CphA2, cyanophycin synthetase, multi-L-arginyl-poly-L-aspartate synthase) is an enzyme with systematic name cyanophycin:L-arginine ligase (ADP-forming).^{[1][2][3][4][5][6]} This enzyme catalyses the following chemical reaction:

ATP + [L-Asp(4-L-Arg)]_n-L-Asp + L-Arg ${\displaystyle \rightleftharpoons }$ ADP + phosphate + [L-Asp(4-L-Arg)]_{n + 1}

Cyanophycin synthase (L-arginine-adding)
Identifiers
EC no.	6.3.2.30
CAS no.	131554-17-1
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

This enzyme requires Mg²⁺ for activity. This enzyme requires Mg²⁺ for activity. All enzymes known to have this activity also catalyze the addition of aspartate, i.e. cyanophycin synthase (L-aspartate-adding) activity. It is structurally similar to Muramyl ligases.