CNGB1

Cyclic nucleotide gated channel beta 1, also known as CNGB1, is a human gene encoding an ion channel protein.^[3]

CNGB1
Identifiers
Aliases	CNGB1, CNCG2, CNCG3L, CNCG4, CNG4, CNGB1B, GAR1, GARP, GARP2, RCNC2, RCNCb, RCNCbeta, RP45, cyclic nucleotide gated channel beta 1, cyclic nucleotide gated channel subunit beta 1
External IDs	OMIM: 600724; HomoloGene: 993; GeneCards: CNGB1; OMA:CNGB1 - orthologs
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16q21 Start 57,882,340 bp[1] End 57,971,128 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in buccal mucosa cell Epithelium of choroid plexus testicle retinal pigment epithelium hypothalamus cingulate gyrus anterior cingulate cortex lateral nuclear group of thalamus entorhinal cortex dorsolateral prefrontal cortex n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding intracellular cyclic nucleotide activated cation channel activity cyclic nucleotide-gated ion channel activity cAMP binding cGMP binding protein binding ligand-gated ion channel activity voltage-gated potassium channel activity intracellular cGMP-activated cation channel activity intracellular cAMP-activated cation channel activity Cellular component integral component of membrane membrane Golgi membrane photoreceptor outer segment ciliary membrane Golgi-associated vesicle membrane transmembrane transporter complex terminal bouton intracellular cyclic nucleotide activated cation channel complex plasma membrane integral component of plasma membrane Biological process protein localization to organelle response to stimulus regulation of rhodopsin mediated signaling pathway regulation of membrane potential cation transport ion transport photoreceptor cell outer segment organization cation transmembrane transport detection of light stimulus involved in visual perception sensory perception of smell retina homeostasis photoreceptor cell maintenance visual perception rhodopsin mediated signaling pathway phototransduction regulation of cytosolic calcium ion concentration potassium ion transmembrane transport protein heterotetramerization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 1258 n/a Ensembl ENSG00000070729 n/a UniProt Q14028 n/a RefSeq (mRNA) NM_001135639 NM_001286130 NM_001297 n/a RefSeq (protein) NP_001129111 NP_001273059 NP_001288 n/a Location (UCSC) Chr 16: 57.88 – 57.97 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

See also

• Cyclic nucleotide-gated ion channel