Cyclomaltodextrinase

The enzyme cyclomaltodextrinase (EC 3.2.1.54) catalyzes the chemical reaction

cyclomaltodextrin + H₂O ${\displaystyle \rightleftharpoons }$ linear maltodextrin

Cyclomaltodextrinase
Identifiers
EC no.	3.2.1.54
CAS no.	37288-41-8
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

It belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is cyclomaltodextrin dextrin-hydrolase (decyclizing). Other names in common use include cycloheptaglucanase, cyclohexaglucanase, and cyclodextrinase. The enzyme participates in starch and sucrose metabolism and acarbose degradation.^[1][2] The cyclomaltodextrinase is capable of degradation of acarbose to glucose and acarviosine-glucose.^[3]

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1EA9 and 1H3G.