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Cyclopyrrolones

Class of chemical compounds From Wikipedia, the free encyclopedia

Cyclopyrrolones
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Cyclopyrrolones are a family of hypnotic and anxiolytic nonbenzodiazepine drugs with similar pharmacological profiles to the benzodiazepine derivatives.

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Skeletal formula of the parent compound, cyclopyrrolone

Although cyclopyrrolones are chemically unrelated to benzodiazepines, they function via the benzodiazepine receptor of neurotransmitter GABA.[1] The best-known cyclopyrrolone derivatives are zopiclone (Imovane) and its active single-enantiomer component, eszopiclone (Lunesta), which are used to treat insomnia, and have a known potential for abuse. Other cyclopyrrolones include:

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