D-sedoheptulose 7-phosphate isomerase

D-sedoheptulose 7-phosphate isomerase (EC 5.3.1.28, sedoheptulose-7-phosphate isomerase, phosphoheptose isomerase, gmhA (gene), lpcA (gene)) is an enzyme with systematic name D-glycero-D-manno-heptose 7-phosphate aldose-ketose-isomerase.^{[1][2][3][4][5]} This enzyme catalyses the following chemical reaction

D-sedoheptulose 7-phosphate ${\displaystyle \rightleftharpoons }$ D-glycero-D-manno-heptose 7-phosphate

D-sedoheptulose 7-phosphate isomerase
Identifiers
EC no.	5.3.1.28
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

In Gram-negative bacteria the enzyme is involved in biosynthesis of ADP-L-glycero-β-D-manno-heptose.