DOTFM-NDEPA

DOTFM-NDEPA is a chemical compound of the phenethylamine, DOx, and NDEPA families.^[1] It is the N-(N,N-diethylpropylamide) (NDEPA) derivative of the psychedelic drug DOTFM.^[1] The drug can also be thought of as a derivative of DOTFM with an LSD-like N,N-diethylamide moiety.^[1] A quantitative structure–activity relationship (QSAR) predicted that DOTFM-NDEPA would bind with high affinity to the serotonin 5-HT_2A receptor.^[1] Its predicted affinity (K_i) was 22 nM.^[1] DOTFM-NDEPA was first described in the scientific literature by 1999.^[1]

DOTFM-NDEPA

Clinical data
Other names	NDEPA-DOTFM; "Compound ko1"[1]
Drug class	Possible serotonin 5-HT2A receptor modulator[1]
ATC code	None
Identifiers
CAS Number	260810-29-5
Chemical and physical data
Formula	C19H29F3N2O3
Molar mass	390.447 g·mol−1
3D model (JSmol)	Interactive image
SMILES C(F)(F)(F)C1C=C(C(=CC=1OC)CC(C)N(CCC(=O)N(CC)CC)[H])OC
InChI InChI=1S/C19H29F3N2O3/c1-6-24(7-2)18(25)8-9-23-13(3)10-14-11-17(27-5)15(19(20,21)22)12-16(14)26-4/h11-13,23H,6-10H2,1-5H3 Key:XQPSNZUNPOQENQ-UHFFFAOYSA-N

See also

• Substituted methoxyphenethylamine
• Partial lysergamide
• DOB-NDEPA
• DOI-NDEPA
• 25D-NM-NDEAOP
• N-DEAOP-NMPEA
• DEMPDHPCA-2C-D