DPDPE

DPDPE ([D-Pen²,D-Pen⁵]enkephalin) is a synthetic opioid peptide and a selective agonist of the δ-opioid receptor (DOR) which is used in scientific research.^[1] It was developed in the early 1980s and was the first highly selective agonist of the DOR to be developed.^[1] It was derived from structural modification of met-enkephalin.^[2]

DPDPE

Clinical data
Other names	L-Tyrosyl-D-penicillamyl-glycyl-L-phenylalanyl-D-penicillamine (2->5)-disulfide; H-Tyr-D-Pen(1)-Gly-Phe-D-Pen(1)-OH
Identifiers
IUPAC name (4S,7S,13S)-13-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid
CAS Number	88373-73-3 Y
PubChem CID	104787
ChemSpider	94592
UNII	HB4QD9GL6F
ChEBI	CHEBI:73356
ChEMBL	ChEMBL31421
CompTox Dashboard (EPA)	DTXSID201008102
Chemical and physical data
Formula	C30H39N5O7S2
Molar mass	645.79 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC1([C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(SS1)(C)C)C(=O)O)CC2=CC=CC=C2)NC(=O)[C@H](CC3=CC=C(C=C3)O)N)C
InChI InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21-,23-,24-/m0/s1 Key:MCMMCRYPQBNCPH-WMIMKTLMSA-N

See also

• DADLE
• DAMGO