DPH-362

DPH-362
Clinical data
Other names	PD129167
Identifiers
	IUPAC name N,N-dimethyl-4,4-diphenylbut-3-en-1-amine;
CAS Number	28916-83-8;
PubChem CID	13465;
ChemSpider	12888;
Chemical and physical data
Formula	C18H21N
Molar mass	251.373 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CN(C)CCC=C(C1=CC=CC=C1)C2=CC=CC=C2;
	InChI InChI=InChI=1S/C18H21N/c1-19(2)15-9-14-18(16-10-5-3-6-11-16)17-12-7-4-8-13-17/h3-8,10-14H,9,15H2,1-2H3; Key:ZRPJJBLGKLVADE-UHFFFAOYSA-N;

DPH-362 is a simplified amitriptyline analog created by omission of the two-carbon dibenzosuberane bridge (the seven membered ring). The resulting compound still had activity in a test to explore TCA sodium channel blockers with analgesic properties.^[1]^[2]

Quick facts Clinical data, Other names ...

It is based on previous structures such as Spasmolytic A29 (one of the active ingredients in Ketogan)^[3]^[4] and SKF-89976A.

See also