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Delftia tsuruhatensis
Species of bacterium From Wikipedia, the free encyclopedia
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Delftia tsuruhatensis is a Gram-negative, rod-shaped, catalase- and oxidase-positive, motile bacterium from the Comamonadaceae family. It was first isolated from a wastewater treatment plant in Japan in 2003.[3] D. tsuruhatensis is an opportunistic and emergent pathogen.[4] All documented human infections are healthcare-associated.[4][5][6]
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Biology and biochemistry
Cells are slightly curved, short rod-shaped cells that occur singly or in pairs. Cells are 0.7–1.2 μm wide and 2.4–4.0 μm long.[3]
D. tsuruhatensis can degrade phenolic compounds[7] and aniline,[8] which are often pollutants of soil and water.
Biofilm interactions
D. tsuruhatensis can inhibit quorum sensing and biofilm formation, which could inform new therapeutic drugs against antibiotic-resistant bacteria.[9] D. tsuruhatensis inhibits quorum sensing and suppresses biofilm formation against Pseudomonas aeruginosa and other pathogens.[9][10] These activities increase P. aeruginosa's susceptibility to antibiotics by 2 to 3 times.[11]
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Applications
In 2023, researchers published evidence in Science that D. tsuruhatensis prevents the development of malaria in mosquitos by secreting harmane. Mosquitos infected by the bacteria had 75% fewer Plasmodium oocysts and featured infection rates one third those of uninfected mosquitoes.[12][13][14][15]
See also
References
External links
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