Top Qs
Timeline
Chat
Perspective
Dihydropteroate
Chemical compound From Wikipedia, the free encyclopedia
Remove ads
Dihydropteroate is an important intermediate in folate biosynthesis. It is a pterin created from para-aminobenzoic acid (PABA) by the enzyme dihydropteroate synthase.[2]

Bacteriostatic agents such as sulfonamides target dihydropteroate synthetase. The effect of dihydropteroate synthetase inhibition is comparable to that of dihydrofolate reductase inhibition by trimethoprim, another bacteriostatic agent. Combinations of these two drug types, such as the combination trimethoprim/sulfamethoxazole or TMP-SMX), are commonly used to treat recurrent urinary tract, Shigella, Salmonella, and Pneumocystis jirovecii infections, though resistance is known.[3]
Remove ads
See also
References
Wikiwand - on
Seamless Wikipedia browsing. On steroids.
Remove ads