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Diisononyl phthalate

Chemical compound From Wikipedia, the free encyclopedia

Diisononyl phthalate
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Diisononyl phthalate (DINP) is a phthalate used as a plasticizer. DINP is typically a mixture of chemical compounds consisting of various isononyl esters of phthalic acid۔

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Use

It is commonly used in a large variety of plastic products including:

  • Plasticizer in polyvinyl chloride (PVC)[2]
  • Construction and building material
  • Fuel and automotive products
  • In electronics materials (as a flexible vinyl additive)[3]
  • As cable insulation additive
  • Adhesives and sealants
  • Paints and coatings
  • Rubber products.

Health issues

The European Union has set a maximum specific migration limit (SML) from food contact materials of 9 mg/kg food for the sum of diisononyl phthalates and diisodecyl phthalates.[4]

DINP is listed as a substance "known to the State of California to cause cancer" under Proposition 65 legislation.[5]

Studies find that exposure to environmentally relevant concentrations of DINP in zebrafish disrupt the endocannabinoid system (ECS) and affect reproduction in a gender specific manner,[6] and have other adverse effects on aquatic organisms, as DINP upregulates orexigenic signals and causes hepatosteatosis together with deregulation of the peripheral ECS and lipid metabolism.[7]

The ECHA's Risk Assessment Committee (RAC) has concluded, on March 7, 2018, that Di-isononyl phthalate (DINP) does not warrant classification for reprotoxic effects under the EU's Classification, Labelling and Packaging (CLP) regulations.[8]

Children and childcare products are strictly regulated by regulatory organizations.[3]

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See also

References

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