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Diisononyl phthalate
Chemical compound From Wikipedia, the free encyclopedia
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Diisononyl phthalate (DINP) is a phthalate used as a plasticizer. DINP is typically a mixture of chemical compounds consisting of various isononyl esters of phthalic acid۔
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Use
It is commonly used in a large variety of plastic products including:
Health issues
The European Union has set a maximum specific migration limit (SML) from food contact materials of 9 mg/kg food for the sum of diisononyl phthalates and diisodecyl phthalates.[4]
DINP is listed as a substance "known to the State of California to cause cancer" under Proposition 65 legislation.[5]
Studies find that exposure to environmentally relevant concentrations of DINP in zebrafish disrupt the endocannabinoid system (ECS) and affect reproduction in a gender specific manner,[6] and have other adverse effects on aquatic organisms, as DINP upregulates orexigenic signals and causes hepatosteatosis together with deregulation of the peripheral ECS and lipid metabolism.[7]
The ECHA's Risk Assessment Committee (RAC) has concluded, on March 7, 2018, that Di-isononyl phthalate (DINP) does not warrant classification for reprotoxic effects under the EU's Classification, Labelling and Packaging (CLP) regulations.[8]
Children and childcare products are strictly regulated by regulatory organizations.[3]
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See also
References
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