Dithizone

Dithizone is a sulfur-containing organic compound. It is a good ligand, and forms complexes with many toxic metals such as lead, thallium^[1] and mercury.

Dithizone

Names
IUPAC name (1E)-3-anilino-1-phenylimino-thiourea
Other names Diphenylthiocarbazone, 1,5-Diphenylthiocarbazone
Identifiers
CAS Number	60-10-6 Y
3D model (JSmol)	Interactive image
ChemSpider	571406 Y
ECHA InfoCard	100.000.413
PubChem CID	657262
UNII	NJZ2CJ4D6P Y
CompTox Dashboard (EPA)	DTXSID0058770
InChI InChI=1S/C13H12N4S/c18-13(16-14-11-7-3-1-4-8-11)17-15-12-9-5-2-6-10-12/h1-10,14H,(H,16,18)/b17-15+ Y Key: UOFGSWVZMUXXIY-BMRADRMJSA-N Y InChI=1/C13H12N4S/c18-13(16-14-11-7-3-1-4-8-11)17-15-12-9-5-2-6-10-12/h1-10,14H,(H,16,18)/b17-15+ Key: UOFGSWVZMUXXIY-BMRADRMJBA
SMILES S=C(/N=N/c1ccccc1)NNc2ccccc2
Properties
Chemical formula	C13H12N4S
Molar mass	256.33 g·mol−1
Melting point	165 to 169 °C (329 to 336 °F; 438 to 442 K)
Hazards
Safety data sheet (SDS)	External MSDS
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y verify (what is YN ?) Infobox references

Dithizone may be prepared by reacting phenylhydrazine with carbon disulfide, followed by reaction with potassium hydroxide.^[2]

Dithizone is used to assess the purity of human pancreatic islet preparations used for transplantation into patients with type 1 diabetes. Dithizone binds zinc ions present in the islet's beta cells, and therefore stains the islets red. Exocrine tissue also present in the preparations does not bind dithizone, and is therefore not stained.

^[3]

• 
  Dithizone
• 
  Dithizone in Ethanol 96%