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Divaricatic acid

Chemical compound From Wikipedia, the free encyclopedia

Divaricatic acid
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Divaricatic acid is a chemical compound with the molecular formula C21H24O7. It is found in a variety of lichens, including some in the genera Evernia,[1] and Lepraria,[2] and Ramalina.[3] It is classified as a depside.

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Divaricatic acid forms colorless crystalline needles with a melting point of 129 °C.[4]

Divaricatic acid has antibacterial properties against some Gram positive bacteria, such as Bacillus subtilis, Staphylococcus epidermidis, Streptococcus mutans, and Enterococcus faecium.[5] Since it also has activity against methicillin-resistant Staphylococcus aureus (MRSA) with a potency equivalent to that of vancomycin, it has been suggested as a potential treatment for MRSA.[5] It also has molluscicidal activity against Biomphalaria glabrata (ram's horn snail) and antiparasitic activity against cercariae of Schistosoma mansoni (blood fluke).[6]

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