EAL domain

In molecular biology, the EAL domain is a conserved protein domain. It is found in diverse bacterial signalling proteins. It is named EAL after its conserved residues. The EAL domain may function as a diguanylate phosphodiesterase.^[1] The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site.

EAL domain
crystal structure of the bacillus subtilis ykui protein, with an eal domain.
Identifiers
Symbol	EAL
Pfam	PF00563
InterPro	IPR001633
CDD	cd01948
Available protein structures: Pfam   structures / ECOD   PDB RCSB PDB; PDBe; PDBj PDBsum structure summary