EMDA-2

Not to be confused with EDMA.

EMDA-2, also known as 2-ethoxy-4,5-methylenedioxyamphetamine, is a psychedelic drug of the phenethylamine and methylenedioxyamphetamine families.^[1][2][3] It is the analogue of MMDA-2 in which the 2-methoxy group has been replaced with a 2-ethoxy group.^[1][2] This has resulted in EMDA-2 being described as the "TWEETIO" analogue of MMDA-2.^[1]

EMDA-2

Clinical data
Other names	2-Ethoxy-MMDA-2; 2-EtO-MMDA-2; 2-Ethoxy-4,5-methylenedioxyamphetamine
Routes of administration	Oral[1][2]
Drug class	Serotonergic psychedelic; Hallucinogen
ATC code	None
Identifiers
IUPAC name 1-(6-ethoxy-1,3-benzodioxol-5-yl)propan-2-amine
PubChem CID	61612198
ChemSpider	34243401
ChEMBL	ChEMBL3246881
Chemical and physical data
Formula	C12H17NO3
Molar mass	223.272 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCOC1=CC2=C(C=C1CC(C)N)OCO2
InChI InChI=1S/C12H17NO3/c1-3-14-10-6-12-11(15-7-16-12)5-9(10)4-8(2)13/h5-6,8H,3-4,7,13H2,1-2H3 Key:OHOFHHFTTSOJCK-UHFFFAOYSA-N

Use and effects

EMDA-2's dose is approximately 135 to 185 mg and its duration is about 10 to 12 hours.^[1][2] At 135 mg, it produced closed eye visuals, including intense colors, with sleep disturbances and a duration of some 10 hours.^[1] At 185 mg, its effects were stronger, including "marvelous" closed-eye visuals with "incredible" colors, good concentration, and distinct body tingles and rushes, with insomnia and a duration of about 12 hours.^[1] The potency of EMDA-2 is about one-third that of MMDA-2.^[1]

History

EMDA-2 appears to have first been described in the scientific literature by at least 1975.^[3] Its effects in humans were described by Alexander Shulgin in his 1991 book PiHKAL (Phenethylamines I Have Known and Loved).^[1][2]

See also

• Substituted methylenedioxyphenethylamine
• Methoxymethylenedioxyamphetamine