Extended synaptotagmin-1

Extended synaptotagmin-1 is a protein in humans that is encoded by the ESYT1 gene.^[5][6][7][8]

ESYT1
Identifiers
Aliases	ESYT1, FAM62A, MBC2, extended synaptotagmin protein 1, extended synaptotagmin 1
External IDs	OMIM: 616670; MGI: 1344426; HomoloGene: 40794; GeneCards: ESYT1; OMA:ESYT1 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q13.2 Start 56,118,250 bp[1] End 56,144,674 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 D3 Start 128,345,834 bp[2] End 128,361,740 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in abdominal fat granulocyte right uterine tube gastric mucosa body of uterus subcutaneous adipose tissue right coronary artery Descending thoracic aorta popliteal artery tibial arteries Top expressed in granulocyte lip esophagus muscle of thigh zygote ascending aorta thymus pharynx tail of embryo aortic valve More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding metal ion binding lipid binding identical protein binding calcium ion binding calcium-dependent phospholipid binding phosphatidylethanolamine binding phosphatidylcholine binding phosphatidylinositol binding Cellular component organelle membrane contact site integral component of membrane integral component of endoplasmic reticulum membrane plasma membrane membrane endoplasmic reticulum endoplasmic reticulum membrane intracellular membrane-bounded organelle intrinsic component of endoplasmic reticulum membrane extrinsic component of cytoplasmic side of plasma membrane Biological process lipid transport glycosphingolipid metabolic process transport endoplasmic reticulum-plasma membrane tethering Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23344 23943 Ensembl ENSG00000139641 ENSMUSG00000025366 UniProt Q9BSJ8 Q3U7R1 RefSeq (mRNA) NM_015292 NM_001184796 NM_011843 RefSeq (protein) NP_001171725 NP_056107 NP_035973 Location (UCSC) Chr 12: 56.12 – 56.14 Mb Chr 10: 128.35 – 128.36 Mb PubMed search [3] [4]
Wikidata
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