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EcpR1 sRNA

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EcpR1 (elongated cell phenotype RNA1) is a trans-encoded small non-coding RNA in the plant-symbiotic Sinorhizobium meliloti, previously named SmelC291, SmrC10, or Sra33.[1][2][3] According to its overproduction phenotype it was renamed Elongated Cell Phenotype RNA1.[4] Induced by stress, EcpR1 negatively regulates cell cycle master regulatory genes dnaA and gcrA at post-transcriptional level by base pairing between its strongly conserved GC-rich loop and the target mRNAs. It is suggested that EcpR1 connects stress adaptation and cell cycle progression.[4]

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