Enah/Vasp-like

Ena/VASP-like protein is a member of the Ena/VASP family of proteins that in humans is encoded by the EVL gene.^[5][6][7]

EVL
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1QC6
Identifiers
Aliases	EVL, RNB6, Enah/Vasp-like
External IDs	OMIM: 616912; MGI: 1194884; HomoloGene: 56752; GeneCards: EVL; OMA:EVL - orthologs
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q32.2 Start 99,971,449 bp[1] End 100,144,236 bp[1]
Gene location (Mouse) Chr. Chromosome 12 (mouse)[2] Band 12|12 F1 Start 108,520,979 bp[2] End 108,654,775 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte right hemisphere of cerebellum ganglionic eminence right frontal lobe anterior cingulate cortex lymph node nucleus accumbens prefrontal cortex anterior pituitary caudate nucleus Top expressed in mesenteric lymph nodes dorsomedial hypothalamic nucleus Gonadal ridge ganglionic eminence ventricular zone molar lateral hypothalamus habenula mandibular prominence dorsal tegmental nucleus More reference expression data BioGPS n/a
Gene ontology Molecular function profilin binding SH3 domain binding protein binding actin binding Cellular component cytoplasm cytosol cell projection membrane focal adhesion cytoskeleton lamellipodium phagocytic vesicle Biological process positive regulation of actin filament polymerization negative regulation of ruffle assembly actin filament organization nervous system development axon guidance cell surface receptor signaling pathway animal organ morphogenesis actin polymerization or depolymerization protein homotetramerization negative regulation of epithelial cell migration positive regulation of stress fiber assembly actin nucleation cellular response to interferon-gamma Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51466 14026 Ensembl ENSG00000196405 ENSMUSG00000021262 UniProt Q9UI08 P70429 RefSeq (mRNA) NM_016337 NM_001330221 NM_001163394 NM_001163395 NM_001163396 NM_007965 RefSeq (protein) NP_001317150 NP_057421 NP_001156866 NP_001156867 NP_001156868 NP_031991 Location (UCSC) Chr 14: 99.97 – 100.14 Mb Chr 12: 108.52 – 108.65 Mb PubMed search [3] [4]
Wikidata
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