Enterovirus 5′ cloverleaf cis-acting replication element

The Enterovirus 5′ cloverleaf cis-acting replication element is an RNA element found in the 5′ UTR of Enterovirus genomes. The element has a cloverleaf like secondary structure and is known to be a multifunctional cis-acting replication element (CRE), required for the initiation of negative strand RNA synthesis.^[1]

Enterovirus 5′ cloverleaf cis-acting replication element
Predicted secondary structure and sequence conservation of Entero_5_CRE
Identifiers
Symbol	Entero_5_CRE
Rfam	RF00386
Other data
RNA type	Cis-reg
Domain(s)	Viruses
SO	SO:0000233
PDB structures	PDBe

See also

• Enteroviral 3′ UTR element
• Enterovirus cis-acting replication element