Estrone methyl ether

Estrone methyl ether
Clinical data
Other names	Oestrone methyl ether; Estrone 3-methyl ether; 3-Methoxyestrone; 3-Methoxyestra-1,3,5(10)-trien-17-one
Drug class	Estrogen; Estrogen ether
Identifiers
	IUPAC name (8R,9S,13S,14S)-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one;
CAS Number	1624-62-0 ; 1091-94-7;
PubChem CID	92895;
UNII	4SMZ4A51IJ;
ChEMBL	ChEMBL1409077;
CompTox Dashboard (EPA)	DTXSID40167368 ;
ECHA InfoCard	100.015.104
Chemical and physical data
Formula	C19H24O2
Molar mass	284.399 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CCC4=C3C=CC(=C4)OC;
	InChI InChI=1S/C19H24O2/c1-19-10-9-15-14-6-4-13(21-2)11-12(14)3-5-16(15)17(19)7-8-18(19)20/h4,6,11,15-17H,3,5,7-10H2,1-2H3/t15-,16-,17+,19+/m1/s1; Key:BCWWDWHFBMPLFQ-VXNCWWDNSA-N;

Estrone methyl ether, or estrone 3-methyl ether, is a synthetic estrogen and estrogen ether – specifically, the C3 methyl ether of estrone – which was never marketed.^[1]^[2] It has been used to synthesize mestranol (ethinylestradiol 3-methyl ether).^[3]

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See also