Etanidazole

Etanidazole is a nitroimidazole drug that was investigated in clinical trials for its radiosensitizing properties in cancer treatment. Administration of etanidazole results in a decrease of glutathione concentration and inhibits glutathione S-transferase.^[1][2] The result is that tissues become more sensitive to the ionizing radiation.^[3]

Etanidazole

Names
Preferred IUPAC name N-(2-Hydroxyethyl)-2-(2-nitro-1H-imidazol-1-yl)acetamide
Identifiers
CAS Number	22668-01-5 N
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL47405 Y
ChemSpider	3161 Y
DrugBank	DB12736
ECHA InfoCard	100.164.363
PubChem CID	3276
UNII	30DKA3Q1HL Y
CompTox Dashboard (EPA)	DTXSID8045434
InChI InChI=1S/C7H10N4O4/c12-4-2-8-6(13)5-10-3-1-9-7(10)11(14)15/h1,3,12H,2,4-5H2,(H,8,13) Y Key: WCDWBPCFGJXFJZ-UHFFFAOYSA-N Y
SMILES O=[N+]([O-])c1nccn1CC(=O)NCCO
Properties
Chemical formula	C7H10N4O4
Molar mass	214.181 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

See also

• 18F-EF5, a related nitroimidazole
• Misonidazole