Top Qs
Timeline
Chat
Perspective

Ethylmagnesium bromide

Chemical compound From Wikipedia, the free encyclopedia

Ethylmagnesium bromide
Remove ads

Ethylmagnesium bromide is a Grignard reagent with formula CH3CH2MgBr, often abbreviated to EtMgBr, where Et is ethyl group. It is widely used in the laboratory synthesis of organic compounds.

Quick facts Identifiers, Properties ...
Remove ads

Reactions

Apart from acting as the synthetic equivalent of an ethyl anion synthon for nucleophilic addition, ethylmagnesium bromide may be used as a strong base to deprotonate various substrates such as alkynes:[1]

RC≡CH + EtMgBr → RC≡CMgBr + EtH

In this application, ethylmagnesium bromide has been supplanted by the wide availability of organolithium reagents.

Preparation

Ethylmagnesium bromide is commercially available, usually as a solution in diethyl ether or tetrahydrofuran. It may be prepared in the normal manner of Grignard reagents by reacting bromoethane with magnesium in diethyl ether:[2]

EtBr + Mg → EtMgBr

References

Loading related searches...

Wikiwand - on

Seamless Wikipedia browsing. On steroids.

Remove ads