Ethylmorphine

Ethylmorphine (also known as codethyline, dionine, and ethyl morphine) is an opioid analgesic and antitussive.^{[2][3][4][5][6][7]}

Ethylmorphine

Clinical data
Trade names	Cosylan, Diolan, Dionina, Diosan, Solvipect, Trachyl
AHFS/Drugs.com	International Drug Names
ATC code	R05DA01 (WHO) S01XA06 (WHO)
Legal status
Legal status	BR: Class A2 (Narcotic drugs)[1] CA: Schedule I DE: Prescription only (Anlage II for higher doses) UK: Class B US: Schedule II and Schedule III (In Combination Products) UN: Narcotic Schedule III
Identifiers
IUPAC name 7,8-didehydro-4,5-α-epoxy- 3-ethoxy-17-methylmorphinan-6-α-ol
CAS Number	76-58-4 Y
PubChem CID	5359271
DrugBank	DB01466 Y
ChemSpider	4514250 Y
UNII	RWO67D87EU
KEGG	D07929
CompTox Dashboard (EPA)	DTXSID1046760
ECHA InfoCard	100.000.883
Chemical and physical data
Formula	C19H23NO3
Molar mass	313.397 g·mol−1
3D model (JSmol)	Interactive image
SMILES O[C@H]2\C=C/[C@H]5[C@@H]4N(CC[C@@]51c3c(O[C@H]12)c(OCC)ccc3C4)C
InChI InChI=1S/C19H23NO3/c1-3-22-15-7-4-11-10-13-12-5-6-14(21)18-19(12,8-9-20(13)2)16(11)17(15)23-18/h4-7,12-14,18,21H,3,8-10H2,1-2H3/t12-,13+,14-,18-,19-/m0/s1 Y Key:OGDVEMNWJVYAJL-LEPYJNQMSA-N Y
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Side effects

Adverse effects are similar to other opioids and include drowsiness, constipation, vertigo, nausea, vomiting, and respiratory depression. Contraindications include asthma, respiratory insufficiency, and age under 8. Ethylmorphine may affect the user's ability to drive and operate heavy machinery, and may cause chemical dependence or addiction at high doses.^[8]

Society and culture

Ethylmorphine was first marketed in France in 1953 by Houde, and in Norway and Spain in 1960. It is not marketed in the United States and is a Schedule II controlled substance.^[8][9]

See also

• Codeine
• Dihydrocodeine
• Morphine
• Pholcodine