Etofenamate

Etofenamate is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of joint and muscular pain.^[1] It is available for topical application as a cream, a gel or as a spray.

Etofenamate

Clinical data
AHFS/Drugs.com	International Drug Names
Routes of administration	Topical (cream, gel, spray)
ATC code	M02AA06 (WHO)
Legal status
Legal status	In general: Over-the-counter (OTC)
Pharmacokinetic data
Protein binding	98–99%
Metabolites	Flufenamic acid, hydroxyl derivatives
Excretion	35% renal, mostly biliary
Identifiers
IUPAC name 2-(2-hydroxyethoxy)ethyl 2-[ [3-(trifluoromethyl)phenyl]amino]benzoate
CAS Number	30544-47-9 Y
PubChem CID	35375
DrugBank	DB08984 Y
ChemSpider	32560 Y
UNII	KZF0XM66JC
KEGG	D04102 Y
CompTox Dashboard (EPA)	DTXSID2045448
ECHA InfoCard	100.045.650
Chemical and physical data
Formula	C18H18F3NO4
Molar mass	369.340 g·mol−1
3D model (JSmol)	Interactive image
SMILES FC(F)(F)c1cc(ccc1)Nc2ccccc2C(=O)OCCOCCO
InChI InChI=1S/C18H18F3NO4/c19-18(20,21)13-4-3-5-14(12-13)22-16-7-2-1-6-15(16)17(24)26-11-10-25-9-8-23/h1-7,12,22-23H,8-11H2 Y Key:XILVEPYQJIOVNB-UHFFFAOYSA-N Y
(verify)

Etofenamate is acutely toxic if swallowed; it is also very toxic to aquatic life, with long lasting effects.^{[2][unreliable medical source?]}