Etofibrate

Etofibrate is a fibrate. It is a combination of clofibrate and niacin, linked together by an ester bond. In the body, clofibrate and niacin separate and are released gradually, in a manner similar to controlled-release formulations.^[1]

Etofibrate

Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	C10AB09 (WHO)
Pharmacokinetic data
Metabolism	Hydrolyzed to clofibric acid and niacin
Identifiers
IUPAC name 2-[(pyridin-3-yl)carbonyloxy]ethyl 2-(4-chlorophenoxy)-2-methylpropanoate
CAS Number	31637-97-5 Y
PubChem CID	65777
DrugBank	DB08983 Y
ChemSpider	59197 Y
UNII	23TF67G79M
KEGG	D07187 Y
ChEMBL	ChEMBL358150 Y
CompTox Dashboard (EPA)	DTXSID80185521
ECHA InfoCard	100.046.115
Chemical and physical data
Formula	C18H18ClNO5
Molar mass	363.79 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(OCCOC(=O)C(Oc1ccc(Cl)cc1)(C)C)c2cccnc2
InChI InChI=1S/C18H18ClNO5/c1-18(2,25-15-7-5-14(19)6-8-15)17(22)24-11-10-23-16(21)13-4-3-9-20-12-13/h3-9,12H,10-11H2,1-2H3 Y Key:XXRVYAFBUDSLJX-UHFFFAOYSA-N Y
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