Family with sequence similarity 19 (chemokine (C-C motif)-like), member A1

Protein FAM19A1 is a protein that in humans is encoded by the FAM19A1 gene.^[5][6]

TAFA1
Identifiers
Aliases	TAFA1, TAFA-1, Family with sequence similarity 19 (chemokine (C-C motif)-like), member A1, family with sequence similarity 19 member A1, C-C motif chemokine like, FAM19A1, TAFA chemokine like family member 1
External IDs	OMIM: 617495; MGI: 2443695; HomoloGene: 45655; GeneCards: TAFA1; OMA:TAFA1 - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p14.1 Start 68,004,247 bp[1] End 68,545,621 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 D3 Start 96,090,135 bp[2] End 96,634,159 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in middle temporal gyrus endothelial cell Brodmann area 23 pons Brodmann area 46 superior frontal gyrus entorhinal cortex postcentral gyrus primary visual cortex dorsolateral prefrontal cortex Top expressed in piriform cortex subdivision of hippocampus Region I of hippocampus proper hippocampus proper lumbar spinal ganglion dentate gyrus pontine nuclei dentate gyrus of hippocampal formation granule cell primary visual cortex amygdala More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding receptor ligand activity Cellular component endoplasmic reticulum extracellular region extracellular space Biological process regulation of signaling receptor activity neuroblast differentiation regulation of neuroblast proliferation signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 407738 320265 Ensembl ENSG00000183662 ENSMUSG00000059187 UniProt Q7Z5A9 Q7TPG8 RefSeq (mRNA) NM_213609 NM_001252216 NM_182808 RefSeq (protein) NP_001239145 NP_998774 NP_877960 Location (UCSC) Chr 3: 68 – 68.55 Mb Chr 6: 96.09 – 96.63 Mb PubMed search [3] [4]
Wikidata
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This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines that act as regulators of immune and nervous cells.^[6]