Fat storage-inducing transmembrane protein 1

Fat storage-inducing transmembrane protein 1 is a protein that in humans is encoded by the FITM1 gene.^[5]

FITM1
Identifiers
Aliases	FITM1, FIT1, fat storage inducing transmembrane protein 1
External IDs	OMIM: 612028; MGI: 1915930; HomoloGene: 41695; GeneCards: FITM1; OMA:FITM1 - orthologs
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q12 Start 24,130,659 bp[1] End 24,132,849 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14|14 C3 Start 55,813,074 bp[2] End 55,814,411 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in muscle of thigh apex of heart gastrocnemius muscle left ventricle right auricle of heart skeletal muscle tissue right lobe of liver body of pancreas spleen left adrenal gland Top expressed in muscle of thigh temporal muscle triceps brachii muscle sternocleidomastoid muscle extraocular muscle digastric muscle interventricular septum soleus muscle medial head of gastrocnemius muscle tibialis anterior muscle More reference expression data BioGPS n/a
Gene ontology Molecular function molecular function Cellular component integral component of membrane integral component of endoplasmic reticulum membrane endoplasmic reticulum membrane endoplasmic reticulum membrane Biological process lipid storage positive regulation of sequestering of triglyceride phospholipid biosynthetic process lipid droplet organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 161247 68680 Ensembl ENSG00000139914 ENSMUSG00000022215 UniProt A5D6W6 Q91V79 RefSeq (mRNA) NM_203402 NM_026808 RefSeq (protein) NP_981947 NP_081084 Location (UCSC) Chr 14: 24.13 – 24.13 Mb Chr 14: 55.81 – 55.81 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Function

FIT1 belongs to an evolutionarily conserved family of proteins involved in fat storage (Kadereit et al., 2008 [PubMed 18160536]).[supplied by OMIM, May 2008].