FUB-144

FUB-144 (also known as FUB-UR-144) is an indole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB₁ receptor^[1] and has been sold online as a designer drug.^[2] It is an analogue of UR-144 and XLR-11 where the pentyl chain has been replaced with fluorobenzyl.

FUB-144

Legal status
Legal status	CA: Schedule II DE: NpSG (Industrial and scientific use only) UK: Class B US: Schedule I
Identifiers
IUPAC name [1-(4-Fluorobenzyl)-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)methanone
CAS Number	2185863-15-2 Y
PubChem CID	118796439
ChemSpider	30646792
UNII	IWY4W66OKW
CompTox Dashboard (EPA)	DTXSID201016907
Chemical and physical data
Formula	C23H24FNO
Molar mass	349.449 g·mol−1
3D model (JSmol)	Interactive image
SMILES Fc1ccc(cc1)Cn1cc(c2c1cccc2)C(=O)C1C(C1(C)C)(C)C
InChI InChI=1S/C23H24FNO/c1-22(2)21(23(22,3)4)20(26)18-14-25(19-8-6-5-7-17(18)19)13-15-9-11-16(24)12-10-15/h5-12,14,21H,13H2,1-4H3 Key:UXOFEILQVZFLRH-UHFFFAOYSA-N

Legal status

In the United States, FUB-144 was temporarily emergency scheduled by the DEA in 2019.^[3] and made a permanent Schedule I Controlled Substance on April 7, 2022.^[4]

Sweden's public health agency suggested classifying FUB-144 as hazardous substance on March 24, 2015.^[5]

See also

• A-834,735
• AB-005
• FAB-144
• JWH-018
• STS-135