Firocoxib

Firocoxib, sold under the brand names Equioxx and Previcox among others, is a nonsteroidal anti-inflammatory drug of the COX-2 inhibitor (coxib) class, approved for use in horses (Equioxx) and for use in dogs (Previcox).^[2][4][9] Firocoxib was the first COX-2 inhibitor approved by the U.S. Food and Drug Administration for horses.^[10] Firocoxib is not intended or approved for use in human medicine.^{[2][4][5][6][11]}

Firocoxib

Clinical data
Trade names	Equioxx, Previcox
AHFS/Drugs.com	Veterinary Use Veterinary Use
License data	US DailyMed: Firocoxib
Routes of administration	By mouth
ATCvet code	QM01AH90 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) CA: ℞-only[1] UK: POM (Prescription only) US: ℞-only[2][3][4] EU: Rx-only[5][6][7][8]
Identifiers
IUPAC name 3-(Cyclopropylmethoxy)-5,5-dimethyl-4-(4-methylsulfonylphenyl)furan-2-one
CAS Number	189954-96-9 Y
PubChem CID	208910
DrugBank	DB09217 Y
ChemSpider	181008 Y
UNII	Y6V2W4S4WT
KEGG	D03712 Y
ChEBI	CHEBI:76136 N
ChEMBL	ChEMBL69998 Y
CompTox Dashboard (EPA)	DTXSID40870188
Chemical and physical data
Formula	C17H20O5S
Molar mass	336.40 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C2OC(C(=C2\OCC1CC1)\c3ccc(cc3)S(=O)(=O)C)(C)C
InChI InChI=1S/C17H20O5S/c1-17(2)14(12-6-8-13(9-7-12)23(3,19)20)15(16(18)22-17)21-10-11-4-5-11/h6-9,11H,4-5,10H2,1-3H3 Y Key:FULAPETWGIGNMT-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

Firocoxib, manufactured by Merial, was approved for veterinary use in the United States for dogs in July 2004,^[12] and for horses in July 2007, as an oral paste (Equioxx) and July 2016, as tablets.^[13][14]

Firocoxib is also available as a generic medication for horses^[14] and for dogs.^[12]