Fluclorolone

Fluclorolone
Clinical data
Other names	6α-Fluoro-9α,11β-dichloro-16α,17α,21-trihydroxypregna-1,4-diene-3,20-dione
Drug class	Corticosteroid; Glucocorticoid
Identifiers
	IUPAC name (6S,8S,9R,10S,11S,13S,14S,16R,17S)-9,11-Dichloro-6-fluoro-16,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one;
CAS Number	3693-38-7;
PubChem CID	76962649;
ChemSpider	32697416;
UNII	036B9W83KK;
ChEBI	CHEBI:135986;
ChEMBL	ChEMBL3707231;
CompTox Dashboard (EPA)	DTXSID601317985 ;
Chemical and physical data
Formula	C21H25Cl2FO5
Molar mass	447.32 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@H]([C@@]2(C(=O)CO)O)O)C[C@@H](C4=CC(=O)C=C[C@@]43C)F)Cl)Cl;
	InChI InChI=1S/C21H25Cl2FO5/c1-18-4-3-10(26)5-13(18)14(24)6-12-11-7-16(27)21(29,17(28)9-25)19(11,2)8-15(22)20(12,18)23/h3-5,11-12,14-16,25,27,29H,6-9H2,1-2H3/t11-,12-,14-,15-,16+,18-,19-,20-,21-/m0/s1; Key:VTWKPILBIUBMDS-OTJLYDAYSA-N;

Fluclorolone is a synthetic glucocorticoid corticosteroid which was never marketed.^[1]^[2] The acetonide cyclic ketal of fluclorolone, fluclorolone acetonide, in contrast, has been marketed.^[1]^[2]

Quick Facts Clinical data, Other names ...

References