Fungal mating pheromone receptors

Fungal pheromone mating factor receptors form a distinct family of G-protein-coupled receptors.

Fungal pheromone mating factor STE2 GPCR
Structure of a Peptide Segment of the 6th Transmembrane Domain of the Saccharomyces cerevisiae alpha-Factor Receptor.[1]
Identifiers
Symbol	STE2
Pfam	PF02116
InterPro	IPR000366
SCOP2	1pjd / SCOPe / SUPFAM
OPM superfamily	6
OPM protein	2k9p
CDD	cd14939
Available protein structures: Pfam   structures / ECOD   PDB RCSB PDB; PDBe; PDBj PDBsum structure summary PDB 1pjdA:253-269

Function

Mating factor receptors STE2 and STE3 are integral membrane proteins that may be involved in the response to mating factors on the cell membrane.^[2][3][4] The amino acid sequences of both receptors contain high proportions of hydrophobic residues grouped into 7 domains, in a manner reminiscent of the rhodopsins and other receptors believed to interact with G-proteins.