Gamma-aminobutyric acid receptor-associated protein-like 1

Gamma-aminobutyric acid receptor-associated protein-like 1 is a protein in humans encoded by the GABARAPL1 gene.

GABARAPL1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2L8J, 2R2Q
Identifiers
Aliases	GABARAPL1, APG8-LIKE, APG8L, ATG8, ATG8B, ATG8L, GEC1, GABA type A receptor associated protein like 1
External IDs	OMIM: 607420; MGI: 1914980; HomoloGene: 134420; GeneCards: GABARAPL1; OMA:GABARAPL1 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12p13.2 Start 10,212,458 bp[1] End 10,223,128 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 F3 Start 129,510,123 bp[2] End 129,519,309 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Brodmann area 23 endothelial cell middle temporal gyrus Pons parotid gland primary visual cortex lateral nuclear group of thalamus internal globus pallidus superior frontal gyrus kidney tubule Top expressed in Hypothalamus hippocampus proper primary visual cortex superior frontal gyrus dentate gyrus of hippocampal formation granule cell striatum of neuraxis human kidney olfactory bulb cerebellar cortex right kidney More reference expression data BioGPS n/a
Gene ontology Molecular function GABA receptor binding Tat protein binding protein binding beta-tubulin binding ubiquitin protein ligase binding Cellular component cytoplasm cell body Golgi apparatus membrane intracellular anatomical structure dendrite membrane autophagosome endoplasmic reticulum mitochondrion dendrite cytoplasm microtubule cytoskeleton cytoplasmic vesicle membrane cytoplasmic vesicle autophagosome membrane cytosol Biological process autophagy macroautophagy autophagosome maturation autophagosome assembly autophagy of mitochondrion cellular response to nitrogen starvation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23710 57436 Ensembl ENSG00000139112 ENSMUSG00000030161 UniProt Q9H0R8 Q8R3R8 RefSeq (mRNA) NM_031412 NM_001363598 NM_020590 RefSeq (protein) NP_113600 NP_001350527 NP_065615 Location (UCSC) Chr 12: 10.21 – 10.22 Mb Chr 6: 129.51 – 129.52 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse