Top Qs
Timeline
Chat
Perspective
Gem-associated protein 4
Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia
Remove ads
Gem-associated protein 4 is a protein that in humans is encoded by the GEMIN4 gene.[5][6]
Remove ads
Remove ads
Function
The product of this gene is part of the SMN protein complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies (gems). The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.[6]
Remove ads
Interactions
GEMIN4 has been shown to interact with:
References
Further reading
Wikiwand - on
Seamless Wikipedia browsing. On steroids.
Remove ads