GLPG-0492

GLPG-0492 (DT-200) is a drug which acts as a selective androgen receptor modulator (SARM). It has been investigated for the treatment of cachexia and muscular dystrophy.^{[1][2][3][4][5][6]}

GLPG-0492

Legal status
Legal status	US: Investigational new drug
Identifiers
IUPAC name 4-[(4R)-4-(hydroxymethyl)-3-methyl-2,5-dioxo-4-phenylimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile
CAS Number	1215085-93-0
PubChem CID	59317173
ChemSpider	28669946
ChEMBL	ChEMBL2178101
Chemical and physical data
Formula	C19H14F3N3O3
Molar mass	389.334 g·mol−1
3D model (JSmol)	Interactive image
SMILES CN1C(=O)N(C(=O)[C@]1(CO)C2=CC=CC=C2)C3=CC(=C(C=C3)C#N)C(F)(F)F
InChI InChI=1S/C19H14F3N3O3/c1-24-17(28)25(14-8-7-12(10-23)15(9-14)19(20,21)22)16(27)18(24,11-26)13-5-3-2-4-6-13/h2-9,26H,11H2,1H3/t18-/m0/s1 Key:VAJGULUVTFDTAS-SFHVURJKSA-N

See also

• ACP-105
• Enobosarm
• JNJ-28330835
• Ligandrol