GPR120 compound A

GPR120 compound A is an experimental drug which acts as a potent and highly selective agonist for the free fatty acid receptor FFAR4 (GPR120). It has antiinflammatory effects and regulates glucose homeostasis and insulin release. It has been researched in animal models of diabetes. GPR120 compound A has also been referred to as GPR120 agonist III but this has also been used in some papers to refer to the older compound TUG-891, which may cause confusion about which drug was used if the chemical structure or other unique identifiers are not specifically stated.^[1][2][3]

GPR120 compound A

Identifiers
IUPAC name 2-[3-[2-chloro-5-(trifluoromethoxy)phenyl]-3-azaspiro[5.5]undecan-9-yl]acetic acid
CAS Number	1599477-75-4
PubChem CID	73777063
IUPHAR/BPS	8418
ChemSpider	35033244
ChEMBL	ChEMBL3919973
Chemical and physical data
Formula	C19H23ClF3NO3
Molar mass	405.84 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1CC2(CCC1CC(=O)O)CCN(CC2)C3=C(C=CC(=C3)OC(F)(F)F)Cl
InChI InChI=1S/C19H23ClF3NO3/c20-15-2-1-14(27-19(21,22)23)12-16(15)24-9-7-18(8-10-24)5-3-13(4-6-18)11-17(25)26/h1-2,12-13H,3-11H2,(H,25,26) Key:WUJVPELCYCESAP-UHFFFAOYSA-N