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Giant solitary trichoepithelioma

Medical condition From Wikipedia, the free encyclopedia

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Giant solitary trichoepithelioma is a cutaneous condition characterized by a skin lesion that may be up to several centimetres in diameter.[1]:672

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Signs and symptoms

Giant solitary trichoepithelioma primarily affects the perianal and groin region.[2] They typically measure a few centimeters in diameter and rarely reach 2 to 3 cm.[3]

Diagnosis

Giant solitary trichoepithelioma is distinguished histologically by a dermal or subcutaneous tumor made up of basophilic cells grouped in solid, adenoid, or lace-like clusters. The cells have a sparse cytoplasm and a darkly pigmented nucleus, and the tumor islands exhibit the typical peripheral cell palisading. Papillary bodies and trichilemmal keratinization in horn cysts are indicative of a solid diagnosis, however they are not always present. Failures to develop papillary mesenchyme are represented by papillary bodies.[4]

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Treatment

The preferred course of treatment is either radiosurgical ablation or surgical excision, with or without a flap.[4]

See also

References

Further reading

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