Glicaramide

Glicaramide (SQ-65993) is an orally bioavailable anti-diabetic medication.^[1] It has a similar potency as glibenclamide (glyburide) in the class of medication known as sulfonylureas. Its structure is similar since it has a cyclic acyl group which replaces the latter's 2-methoxy-5-chlorobenzyl.^[2] Same as glibenclamide, it is classified as a second-generation sulfonylurea. It may have more pronounced extra-pancreatic effects than glibenclamide or tolbutamide.^[2]

Glicaramide

Clinical data
ATC code	None
Identifiers
IUPAC name N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-1-ethyl-3-methyl-4-(3-methylbutoxy)pyrazolo[3,4-b]pyridine-5-carboxamide
CAS Number	36980-34-4
PubChem CID	65799
ChemSpider	59215
UNII	UK5SR22C8Q
ChEMBL	ChEMBL2106430
CompTox Dashboard (EPA)	DTXSID60190471
Chemical and physical data
Formula	C30H42N6O5S
Molar mass	598.76 g·mol−1
3D model (JSmol)	Interactive image
SMILES C0CCCCC0NC(=O)NS(=O)(=O)c1ccc(cc1)CCNC(=O)c2cnc3n(CC)nc(C)c3c2OCCC(C)C

See also

• Glibenclamide