Glucosylceramide beta-1,4-galactosyltransferase

Glucosylceramide beta-1,4-galactosyltransferase (EC 2.4.1.274, lactosylceramide synthase, uridine diphosphate-galactose:glucosyl ceramide beta 1-4 galactosyltransferase, UDP-Gal:glucosylceramide beta1->4galactosyltransferase, GalT-2, UDP-galactose:beta-D-glucosyl-(1<->1)-ceramide beta-1,4-galactosyltransferase) is an enzyme with systematic name UDP-alpha-D-galactose:beta-D-glucosyl-(1<->1)-ceramide 4-beta-D-galactosyltransferase.^{[1][2][3][4][5]} This enzyme catalyses the following chemical reaction

UDP-alpha-D-galactose + beta-D-glucosyl-(1<->1)-ceramide ${\displaystyle \rightleftharpoons }$ UDP + beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide

Glucosylceramide beta-1,4-galactosyltransferase
Identifiers
EC no.	2.4.1.274
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
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Involved in the synthesis of several different major classes of glycosphingolipids.