Glycerophosphodiester phosphodiesterase

The enzyme glycerophosphodiester phosphodiesterase ({EC 3.1.4.46)^[1] catalyzes the reaction

a glycerophosphodiester + H₂O ${\displaystyle \rightleftharpoons }$ an alcohol + sn-glycerol 3-phosphate

glycerophosphodiester phosphodiesterase
Identifiers
EC no.	3.1.4.46
CAS no.	86280-59-3
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Glycerophosphodiester phosphodiesterase
Identifiers
Symbol	GDP
Pfam	PF03009
Membranome	584
Available protein structures: Pfam   structures / ECOD   PDB RCSB PDB; PDBe; PDBj PDBsum structure summary

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name is glycerophosphodiester glycerophosphohydrolase. Other names in common use include gene hpd protein, glycerophosphoryl diester phosphodiesterase, and IgD-binding protein D. This enzyme participates in glycerophospholipid metabolism.