HZ-2

HZ-2 is a drug which acts as a highly selective κ-opioid agonist.^[1] It is a potent analgesic with around the same potency as morphine, with a long duration of action and high oral bioavailability.^[2][3] Side effects include sedation, nausea and dysphoria as well as diuretic effects.^[4]

HZ-2

Identifiers
IUPAC name Dimethyl 3,7-dimethyl-9-oxo-2,4-dipyridin-2-yl-3,7-diazabicyclo[3.3.1]nonane-1,5-dicarboxylate
CAS Number	253304-60-8
PubChem CID	356604
CompTox Dashboard (EPA)	DTXSID90326741
Chemical and physical data
Formula	C23H26N4O5
Molar mass	438.484 g·mol−1
3D model (JSmol)	Interactive image
SMILES n3ccccc3C(N1C)C2(C(=O)OC)CN(C)CC(C2=O)(C(=O)OC)C1c4ccccn4
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