Hegedus indole synthesis

The Hegedus indole synthesis is a name reaction in organic chemistry that allows for the generation of indoles through palladium(II)-mediated oxidative cyclization of ortho-alkenyl anilines.^{[1][2][3][4][5][6]} The reaction can still take place for tosyl-protected amines.^[4]

Hegedus indole synthesis
Named after	Louis S. Hegedus
Reaction type	Ring forming reaction

Application

2-Allylaniline can be converted to 2-Methylindole using the Hegedus indole synthesis.^[1]