Hepatic fructokinase

Hepatic fructokinase (or ketohexokinase) is an enzyme that catalyzes the phosphorylation of fructose to produce fructose-1-phosphate.

ATP +  ${\displaystyle \longrightarrow }$  ADP +

ATP + D-fructose → ADP + D-fructose-1-phosphate^[1]

ketohexokinase (fructokinase)
Ketohexokinase homodimer, Human
Identifiers
Symbol	KHK
NCBI gene	3795
HGNC	6315
OMIM	229800
RefSeq	NM_006488
UniProt	P50053
Other data
EC number	2.7.1.3
Locus	Chr. 2 p23.3-23.2
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Ketohexokinase
Identifiers
EC no.	2.7.1.3
CAS no.	9030-50-6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
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Pathology

A deficiency is associated with essential fructosuria.