Azepane

Azepane is the organic compound with the formula (CH₂)₆NH. It is a colorless liquid. A cyclic secondary amine, it is a precursor to several drugs and pesticides. It is produced by partial hydrogenolysis of hexamethylene diamine.^[2]

Azepane

Names
Preferred IUPAC name Azepane
Other names Hexahydroazepine Hexamethyleneimine Homopiperidine Perhydroazepine HMI azacycloheptane
Identifiers
CAS Number	111-49-9 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:32616 Y
ChEMBL	ChEMBL1375444 N
ChemSpider	7828 Y
ECHA InfoCard	100.003.524
PubChem CID	8119
UNII	CZD076G73R Y
CompTox Dashboard (EPA)	DTXSID1026879
InChI InChI=1S/C6H13N/c1-2-4-6-7-5-3-1/h7H,1-6H2 Y Key: ZSIQJIWKELUFRJ-UHFFFAOYSA-N Y InChI=1/C6H13N/c1-2-4-6-7-5-3-1/h7H,1-6H2 Key: ZSIQJIWKELUFRJ-UHFFFAOYAF
SMILES C1CCCNCC1
Properties
Chemical formula	C6H13N
Molar mass	99.177 g·mol−1
Appearance	colorless liquid
Density	0.88 g/cm3[1]
Melting point	−37 °C (−35 °F; 236 K)
Boiling point	138 °C (280 °F; 411 K)[1] (749 mmHg)
Hazards
Flash point	30 °C (86 °F; 303 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

Like many amines, it reacts with carbon dioxide.^[3]

Azepane-containing drugs

A variety of pharmaceutical drugs contain an azepane ring including bazedoxifene, cetiedil, glisoxepide, mecillinam, nabazenil, setastine, and tolazamide, among others.

See also

• Azepine