Hsp17 thermometer

In molecular biology, the Hsp17 thermometer is an RNA element (RNA thermometer) found in the 5' UTR of Hsp17 mRNA.^[1] Hsp17 is a cyanobacterial heat shock protein belonging to the Hsp20 family.^[2]

Hsp17 thermometer
Predicted secondary structure and sequence conservation of PinT small RNA
Identifiers
Rfam	RF02358
Other data
Domain(s)	Bacteria
GO	GO:0009266
SO	SO:0005836
PDB structures	PDBe

At physiological temperature (28 degrees Celsius) the Hsp17 thermometer forms a hairpin structure, preventing translation of Hsp17. Under heat shock conditions the hairpin structure melts and translation takes place.^[1]

See also

• RNA thermometer
• ROSE element
• FourU thermometer
• Hsp90 cis-regulatory element
• Cyanobacterial RNA thermometers